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Study Shows Differences in Left vs. Right Colon in Black vs. White Individuals

DNA methylation is affected by age and environmental exposures. Abnormal DNA methylation is a sign of colorectal cancer. In a comparison between black and white individuals, the right colon seems to age quicker in black people. According to results from a biopsy study, this could explain the higher frequency of right-side colon cancer among African Americans.  Read the original publication of this study here: [Racial Disparities in Epigenetic Aging of the Right vs. Left Colon]  Th

Microbiomes, Botanical Biohacking, and Epigenetics

The impact of medicinal and culinary herbs and botanicals has been studied extensively. The term might be new, but botanical biohacking has been used for centuries to optimize gut health. Gut health has a direct impact on our epigenome. Read on to learn more.    RELATED: How The Environment You Grew Up In Can Have Long Term Effect On Genes   In this article: Microbiomes Biohacking Epigenetics   Use Botanical Biohacking to Support Your Epigenome

Epigenetic Modifications in PEDV

Porcine epidemic diarrhea virus (PEDV), a highly contagious swine coronavirus, first emerged in America in 2013. The outbreak caused high death rates in the pork industry escalating from the US to Mexico and Canada.  Although experts believe PEDV cannot be transmitted to humans, like other coronaviruses, they are noted for their capacity to suspend innate immune response, giving rise to an infection’s persistence and severity.   Despite best efforts, no definite drug treatment has been

New Discovery of Methylation Sites Linked to hATTR Amyloidosis

Hereditary transthyretin (TTR) amyloidosis (hATTR) is a rare, life-threatening disorder caused by amyloidogenic coding mutations located in the TTR gene. To date, more than 130 amyloidogenic mutations have been identified in the coding regions of the TTR gene, which are the cause of the disorder. Previous data strongly support the role of non-coding regulatory variation on TTR gene expression as one of the mechanisms affecting the phenotypic manifestations observed in carriers of TTR a

High-Altitude‌ ‌Living‌ ‌Alters‌ ‌Epigenetics‌ ‌

Human evolution is at work in the Andes mountains. People have evolved genetic adaptations to survive high altitude living. A recent study has highlighted chemical changes that control the activity of that DNA. Read on to learn more.    RELATED: The Link Between Epigenetics And Social Factors   New Studies on High Altitude Living Highlights Chemical Changes That Control the Activity of That DNA Cold temperatures, scarce oxygen, and intense ultraviolet radiation make

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New Gene Therapy Strategy May Delay Aging

Scientists believe that cellular senescence is a rudimentary driver of aging in organisms in a stable arrest state.  Researchers Wang et al., in collaboration with the Institute of Zoology of the Chinese Academy of Sciences (CAS), Peking University, and Beijing Institute of Genomics of CAS, have teamed up to find new human senescence-promoting genes.  Using a screening system known as CRISPR/Cas9, the team has shed new light on aging regulation. Read the original publication of th

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Weight loss and Epigenetics: BPA Might Change Fat Cells but Is Not Permanent

A recent study looks at the effect of Bisphenol-A (BPA) on obesity, weight loss, and epigenetics. The findings could change the way we approach weight loss and epigenetics.  RELATED: Obesogenic Diet Drives Epigenetic Predisposition To Metabolic Disorders In this article: Background Study Methods and Results Conclusion Study Uncovers Potential for Weight Loss and Epigenetics  Background Obesity is on the rise, but despite attempts to find the unde

Restore Eyesight By Turning Back Epigenetic Clock

A recent study published in Nature claims that scientists can restore eyesight to a youthful state. Read on to learn more.  RELATED: Epigenetic Clock May Predict Brain Aging and Dementia In this article: Background Studies Findings Summary Points   Can Science Really Restore Eyesight? Background Throughout our lifetime, DNA methylation and other epigenetic changes effectively switch genes on or off in specific tissues. As gene expression

SARS-CoV-2 and The Implications of Lifestyle and Aging

Aging and lifestyle factors increase susceptibility to SARS-CoV-2. A healthy lifestyle may also improve mitochondrial health. Therefore, lifestyle may be crucial in resisting the virus. RELATED: Epigenetic Modifications -- Can Scientists Turn Off SARS-CoV-2? In this article: Lifestyle Increase SARS-CoV-2 Risk Mitochondrial Health Exercise and Immune Function Therapeutic Strategy   Lifestyle Increase SARS-CoV-2 Risk The risk of severe infection

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Female Fertility Linked to Biological Age According to Study

A recent study found fertility linked to biological age. We take a closer look at the findings and possible implications. RELATED: The 6 Best Ways To Disturb Patterns of Methylation In this article: Background and Study Overview Study Findings: Fertility Linked to Biological Age Implications and Conclusion   Background and Study Overview Between 9% and 24% of patients undergoing ovarian stimulation for in vitro fertilization (IVF) have an inadequ

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Alzheimer's Disease: How Epigenetics Is Changing What We Know

Advances in Alzheimer's disease have been a long time coming. After two decades without new medication, epigenetics is changing our approach, and some of the mysteries surrounding this disease are beginning to open up. We hope to soon gain new insights into ways to end the disease. RELATED: How To Optimize Brain Health And Longevity With Epigenetics In this article: A New Approach To Alzheimer's Disease Recent Findings Tau Protein and Epigenetics   A New A

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Epigenetic Clock May Predict Brain Aging and Dementia

Researchers hope to shine a light on brain aging and dementia with a new epigenetic clock, a critical component in preventing, slowing, or even reversing traits related to aging. RELATED: Epigenetics And Aging: How Some People Are Able To Age Better In this article: Brain Aging and Dementia DNA Methylation and Brain Aging New Cortical Clock Brain Aging and Dementia Our brains age at different rates.  Where chronological age is the number of years

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Cancer Prediction Is Improving Thanks to New Algorithm

Using a new algorithm, researchers reveal a previously undetected collection of cancer driver genes. As a result, our knowledge of epigenetic mechanisms in tumorigenesis and cancer prediction is improving. RELATED: Machine Learning and Clinical Epigenetics In this article: Cancer Driver Genes DORGE Algorithm How Cancer Prediction Is Improving   Cancer Driver Genes Cancers stem from a build-up of genetic changes in the DNA of normal cells. These

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The Link Between Epigenetics and Social Factors

The US, Republic of Ireland, and Northern Ireland will join forces on a new project that looks at how psychological, behavioral, environmental, and social factors in childhood impact gene expression, aging, and health later in life. RELATED: Hallmarks of Aging In this article: Epigenetics and Social Factors Project  Longitudinal Studies From Each Country   Epigenetics and Social Factors Project  Stressful events like violence, neglect, and hunger in chi

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Novel Epigenetic Clock Study in Rats Utilizes Phenotypic Data to Identify Biomarkers of Aging

The study identifies epigenetic changes that correlate strongly with observed age in rats. It also details physical performance independent of cell makeup and age. Moreover, it shows that interventions such as caloric restriction(CR) and cellular reprogramming impact mammalian aging. RELATED: 3 Things You Can Learn From An Epigenetic Blood DNA Test In this article: Rat Epigenetic Clock Study Background Rat Epigenetic Clock Study Findings Study Conclusion

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Antiretroviral Therapy Leaves Patients More Susceptible to Aging-Related Illnesses

A new study from UCLA shows that antiretroviral therapy given to patients over two years was unable to restore age-appropriate epigenetic patterns. The results mean suggest that patients are experience rapid aging and are more likely to suffer from aging-related illnesses. RELATED: Epigenetic Marks: What They Are, and Why They Matter In this article: Epigenetics Antiretroviral Therapy Prior Research The Study Background Method Results

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Researchers Discover DNA in Umbilical Cord Can Diagnose Autism Early

Researchers have discovered biomarkers of autism in the umbilical cord, which could aid physicians in making an early diagnosis of autism spectrum disorder (ASD), and thus create intervention strategies.  RELATED: Study Shows The Older A Person Is When They Give Birth, The Older They May Live  In this article: What Is Autism? What Are The Symptoms of Autism? Why Is Early Diagnosis Important? What Are The Treatments For ASD? Biomarkers of ASD in the Umb

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NT-219 And Advanced Solid Tumors

Kitov Pharma has recently announced new data that supports NT-219 as monotherapy for the treatment of advanced solid tumors.   RELATED: What Is The Role Of Senescent Cells in Aging?   In this article: What is NT-219? Clinical Trials Announcements From Kitov Summary Points   Data Underpins Potential of NT-219 to Overcome Advanced Solid Tumors   Kitov Pharma Ltd. (Kitov) is a clinical-stage drug developer using cutting-edge therapies to overcome

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The 6 Best Ways To Disturb Patterns of Methylation

Too much methylation is a problem as it can cause various disease states and speed up the aging process. However, there are ways we can disturb methylation expression and optimize our health.    RELATED: What Is The Role Of Senescent Cells in Aging?   In this article: Methylation Expression and Aging 6 Ways to Disturb Methylation Expression Get Essential Nutrients Eat Foods Rich in Methylation Adaptogens Reduce Calorie Intake Limit Alcohol Consumption Ge

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Are Pandemic Requirements Changing the Epigenetic Regulation of Your Skin?

The global pandemic has changed almost every factor of people’s lives. From economic devastation to peoples' music taste, the world has been dramatically impacted by COVID-19 by altering our lives in many different ways.  Believe it or not, COVID-19 has even had an impact on the body's largest organ- the virus is changing the skin's epigenetic regulation.   RELATED: What Is The Role Of Senescent Cells in Aging?   In this article: How the Pandemic Has Caused Physical Skin Changes

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Epigenetics and Anxiety - The Relationship Between Genes and Stress-Related Disorders

Epigenetics and anxiety have a scientifically-backed relationship. Increasing numbers of studies show that stress-related disorders, like anxiety, are contributed by abnormalities in epigenetic mechanisms of gene expression. RELATED: We Can Now Turn Back the Biological Clock: 5 Advantages of Epigenetics In this article: Anxiety Disorders (ADs) Scope Epigenetics and Anxiety Pathogenesis Implications of Epigenetic Drugs in Anxiety Disorders Trials of Epigenetic

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Mice With Longer Telomeres Show Longer Lifespans

One animal study shows a link between telomere length and metabolic aging. Read on to learn all about it.   RELATED: How To Turn Back Your Biological Clock? Know Your Epigenetic Biomarkers In this article: What Are Telomeres? How Are They Linked to the Lifespan? Are there Ways to Lengthen Telomeres? What Happens When You Lengthen Telomeres in Mice? Telomere Length and Metabolic Aging: What You Need to Know What Are Telomeres? Telomeres are prot

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What is a Telomere, and How Is It Linked to Longevity?

Research shows a link between telomere length and longevity. Read on to learn more about telomeres.   RELATED: New Study Shows A Body’s Biological Age Can Be Reversed   In this article: What Is a Telomere? Why Are Telomeres Important? How Are They Linked to Longevity and Aging? What Contributes to Telomere Shortening? Are There Other Telomere Interventions? What’s Next?   Everything You Need to Know About Telomere and Longevity   What Is a Te

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Study Shows The Older A Person Is When They Give Birth, The Older They May Live

A new study shows the link between longevity, maternal age, and leukocyte telomere length. Read on to learn about these exciting new findings.  RELATED: Epigenetics And Aging: How Some People Are Able To Age Better In this article: Telomere Length and Lifespan New Study: Maternal Age and Leukocyte Telomere Length Other Epigenetic Applications New Study Alert: The Association Between Maternal Age, Leukocyte Telomere Length, and Lifespan Longevity Telomere Lengt

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Improve Sperm Health With These 9 Epigenetic Factors

Understanding sperm epigenetics may help improve your reproductive health. Read on to learn all about it.  RELATED: How Does An Epigenome Work? Understanding The Critical Element In Aging In this article: Decline of Sperm Health Sperm Quality and Epigenetics 9 Tips For Healthier Sperm Epigenetics Sperm Epigenetics: 9 Tips For Healthier Swimmers Decline of Sperm Health   Normally, we associate sperm health with sperm count or the quantity of

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